Arizona Cardinals
- 2025 NFL Team Betting Analysis

The Cardinals close out 2025 on a brutal betting skid. They have dropped their last five games ATS and gone 1-8-1 over the previous ten, with the single cover coming as 2.5-point underdogs at Dallas. Totals have leaned slightly higher in that stretch (6-4 overs), but the consistent inability to beat the number has defined their recent form.

For the full season Arizona finished 5-11-1 ATS and 10-7 to the over. As favorites in just three games they covered only once. The bulk of their action came as double-digit underdogs, where they posted just one ATS win. Home performance was especially poor at 1-6 ATS, while the road mark improved modestly to 4-5. The Cardinals led at halftime in only six of 17 games and led after the first quarter at the same 35 percent clip, indicating they rarely built early cushions and were frequently chasing.

The clearest standout result came in Week 9 when Arizona covered a modest 2.5-point spread at Dallas by ten points, their largest margin cover of the year. Most other positive ATS outcomes were narrow wins or pushes as underdogs, while heavy home losses repeatedly produced large margins against the number.

The current betting angle is straightforward: Arizona offers little value at home, where they have been one of the league’s worst ATS teams. Road underdog spots have produced their only modest success, but the late-season collapse suggests even those spots carry elevated risk. Overs have been the more reliable total-side lean, particularly when the Cardinals are forced into negative game scripts.